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health advisory Hospital Mental Health 2007-11-15 19:01:00

Serotonin, norepinephrine and acetylcholine are among the chemical messengers in these circuits that play a role in the regulation of emotions, including sadness, anger, anxiety and irritability. Drugs that enhance brain serotonin function may improve emotional symptoms in BPD. Likewise, mood-stabilizing drugs that are known to enhance the activity of GABA, the brain's major inhibitory neurotransmitter, may help people who experience BPD-like mood swings. Such brain-based vulnerabilities can be managed with help from behavioral interventions and medications, much like people manage susceptibility to diabetes or high blood pressure.7

Future Progress

Studies that translate basic findings about the neural basis of temperament, mood regulation and cognition into clinically relevant insights鈥攚hich bear directly on BPD鈥攔epresent a growing area of NIMH-supported research. Research is also underway to test the efficacy of combining medications with behavioral treatments like DBT, and gauging the effect of childhood abuse and other stress in BPD on brain hormones. Data from the first prospective, longitudinal study of BPD, which began in the early 1990s, is expected to reveal how treatment affects the course of the illness. It will also pinpoint specific environmental factors and personality traits that predict a more favorable outcome. The Institute is also collaborating with a private foundation to help attract new researchers to develop a better understanding and better treatment for BPD.

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unfortuantly this cannot be treated, i have found out recently i have two types of personaility disorder. It can be cared for and managed, but never cured. I am at the moment doing a group therapy thing. Ive only started this week and it was ok, and i will be going back. I see a psycologist every 3weeks and he has explained to me today about personality disorders. Treating the depression side of it also helps. Although i have been on anti depressants since i was 15, im now 21 nearly 22, i still get bads bouts of depression but they would be much worse if i wasnt taking any medication. But medication doesnt actually cure PD

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