why TCA drugs need 2-3 weeks to produce its action
TCA = tri cyclic antidepressent
Answers:Because they alter chemicals in your brain, and it takes that long for them to build up in your system and stay in your system to get that effect. Nurses call it a "half life". TCA's have a long half life. Meaning that it's half life is half of the time it takes for your body to cleanse the medication out of your system. Where drugs like pain meds have a short half life. In order to work properly the TCA's have to be in your blood at certian levels to affect brain function. In some people they have to be at higher levels than others. You never know your personal level until you take the drugs jfor awhile and alleviate the depression. This is why your doctor may tweak your dosage several times before settling on a fixed dosage of medication.
Here you go, this site should tell you everything you need to know:
http://en.wikipedia.org/wiki/tricyclic_a.
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