Would you please explain me what is TPOX
health advisory
Hospital
Doctor Yu
2007-11-8 19:09:47
It is about DNA testing
Answers:jgrqa
TPOX is a locus found on intron 10 of human thyroid peroxidase gene. TPOX has 2 alleles that are the same and is used for DNA profiling. Others include CSF1PO, THO1, and vWA.
At the TPOX locus, since both alleles are the same there is only one term 鈥?pp or p[.squared.], which represents the combined probability of inheriting the allele 8 from each parent. Hence about 28% of people have the same TPOX genotype as does the evidence. It is to be expected that the proportion of TPOX 8,8 people is still 28% even if attention is restricted only to people who have a particular CSF1PO genotype such as 10,11. Therefore the chance for a person to have the combined genotype in the two loci is 28% of 16% 鈥?about 4%.
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