What does diffuse fatty liver change mean
I have not been well since January. I had an Ultrasound then and it read that I had a fatty liver. To make a long story short, I had a CT with and without contrast done (for kidneys-I have kidney stones) and I ended up having my gallbladder taken out a couple of weeks ago due to large gallstones. Well, I have a copy of my report from the CT scan and it was compared to a previous CT and it read that I have diffuss fatty liver change. What does this mean ? Should I be concerned ? Is this the beginning of Cirrhosis ? Is this something that can end up killing me ? What should I expect next as far as testing is concerned ? I do not drink alcohol nor am I obese. I am going back in four weeks to see my Primary care physician and just wanted some input about this prior to that appointment. Thank you.
Answer:Alcohol is the most common cause. Toxic, metabolic and hypoxic conditions of all types.
Pathogenesis
鈥?Liver is the principle organ of fat metabolism and synthesis.
鈥?Interference with mobilizing triglycerides out of the liver is the usual mechanism.
鈥?This happens when toxins or agents affect the mitochondrial and microsomal functions resulting in defective oxidation of fatty acids and aberrant mitochondrial function.
鈥?Factors casuing fatty change do not all act in the same way. ,
Epidemiology
鈥?This is a common condition, but it is usually secondary to other diseases; again, alcohol is the most common cause, in the industrial world; however, among children and in the developing countries, malnutrition, especially protein and iron deficiencies, are the most common.
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