What chemicals does the body produce when having a heart attack

Following Enzymes/chemicals are secreted:

Cardiac Enzymes

There are several enzymes that are released when heart cells are damaged. A specific, sensitive marker that is present in 1-2 hours after the cardiac muscle injury continues to be sought.

Troponin T and I

These are contractile proteins of the myofibril. The cardiac isoforms are very specific for cardiac injury and are not present in serum from healthy people. Current guidelines from the American College of Cardiology Committee state that cardiac troponins are the prefered markers for detecting myocardial cell injury.

Troponin I (cTnI) or T (cTnT) are the forms frequently assessed.

搂 Rises 2 - 6 hours after injury

搂 Peaks in 12 - 16 hours

搂 cTnI stays elevated for 5-10 days, cTnT for 5-14 days

Creatine Kinase (creatine phosphokinase)

This enzyme is found in heart muscle (CK-MB), skeletal muscle (CK-MM), and brain (CK-BB). Creatine kinase is increased in over 90% of myocardial infarctions. However, it can be increased in muscle trauma, physical exertion, postoperatively, convulsions, delirium tremens and other conditions.

Time sequence after myocardial infarction

搂 begins to rise 4-6 hours

搂 peaks 24 hours

搂 returns to normal in 3-4 days

Creatine Phosphokinase Isoenzymes

搂 MM fraction - skeletal muscle

搂 MB fraction - heart muscle

搂 BB fraction - brain